5-Amino-1MQ Dosage Protocol
Table of Contents
Quickstart Highlights
5-Amino-1MQ dosage protocols center on this selective, cell-permeable NNMT (Nicotinamide N-methyltransferase) inhibitor studied for its potential to support fat metabolism, preserve lean muscle mass, and elevate intracellular NAD+ levels. By blocking NNMT, 5-Amino-1MQ may help restore cellular energy balance and activate SIRT1 pathways associated with metabolic efficiency[3]. This educational protocol presents a subcutaneous injection approach to maximize bioavailability from the limited 10 mg vial format.
- Reconstitute: Add 2.0 mL bacteriostatic water → 5 mg/mL concentration.
- Typical daily range: 2.5–5 mg once or twice daily (subcutaneous).
- Easy measuring: At 5 mg/mL, 1 unit = 0.01 mL = 50 mcg on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F) and use within 2–4 weeks.
Dosing & Reconstitution Guide
Phase
Daily dose (mg)
Units (per injection) (ml)
Frequency: Inject once or twice daily subcutaneously. Due to the compound’s plasma half-life of approximately 3.8–6.9 hours, twice-daily (BID) dosing may provide more sustained NNMT inhibition. Note: A single 10 mg vial provides only 2–4 days of research material at these doses.
Supplies Needed
5-Amino-1MQ Vials (10 mg each):
- 1 week (5 mg/day) ≈ 4 vials
- 2 weeks (5 mg/day) ≈ 7 vials
- 4 weeks (5 mg/day) ≈ 14 vials
- Per week (once daily): 7 syringes
- Per week (BID): 14 syringes
- 4 weeks (once daily): 28 syringes
- 1 week (4 vials): 8 mL → 1 × 10 mL bottle
- 2 weeks (7 vials): 14 mL → 2 × 10 mL bottles
- 4 weeks (14 vials): 28 mL → 3 × 10 mL bottles
Alcohol Swabs:One for the vial stopper + one for the injection site each administration.
- Per week (once daily): 14 swabs
- 4 weeks (once daily): 56 swabs → recommend 1 × 100-count box
